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From DNA to Diversity : Molecular Genetics and the Evolution of Animal Design

By: Carroll, Sean B.
Contributor(s): Grenier, Jennifer | Weatherbee, Scott.
Material type: TextTextSeries: eBooks on Demand.Publisher: Hoboken : Wiley, 2009Edition: 2nd ed.Description: 1 online resource (272 p.).ISBN: 9781444309218.Subject(s): Animal Population Groups | Biological diversity | Evolution, Molecular | Evolutionary genetics | Gene expression | Molecular genetics | Variation (Genetics)Genre/Form: Electronic books.Additional physical formats: Print version:: From DNA to Diversity : Molecular Genetics and the Evolution of Animal DesignDDC classification: 572.8/38 | 572.838 Online resources: Click here to view this ebook. Summary: In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa.Builds logically from developmen
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Electronic Book UT Tyler Online
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QH390.C37 2005 (Browse shelf) http://uttyler.eblib.com/patron/FullRecord.aspx?p=428085 Available EBL428085

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa.Builds logically from developmen

Description based upon print version of record.

Reviews provided by Syndetics

CHOICE Review

In this slim volume, three molecular geneticists place recent findings about genetic similarities between diverse animal lineages into the broad context of animal evolution. The puzzling, and fascinating, sequence of development that transforms embryos into morphologically and functionally complex adults is attributed to the workings of highly conserved hox genes (here called an animal "genetic toolkit") and to the regulatory elements permitting genes to act in spatially and temporally distinct fashions. By pairing sophisticated molecular probe technology with classic taxonomic analysis, the book nicely illustrates how underlying genetic regulatory plasticity (pleiotropy), coupled with gene duplication, can account for the complexity of animal body plans, if not for the diversity of animal forms. The authors even stretch this analysis at one point to speculate on the appearance of the common bilateralist ancestor. Illustrations range from illuminating full-color comparisons of gene and sequence homologies and protein localizations to rather generic evolutionary trees. Chapter references; glossary. This useful book, combining a well-written review of the genetics behind morphological patterning with solid evolutionary analysis, is for a graduate audience, although upper-division undergraduates, faculty, and professionals would also profit from its clear and thorough presentation. S. K. Sommers Smith Boston University

Author notes provided by Syndetics

Sean B. Carroll is currently an investigator of the Howard Hughes Medical Institute and Professor of Molecular Biology and Genetics at the University of Wisconsin. His research for the past twenty years has focused on the genetics of animal development and evolution, and yielded many original discoveries as to the mechanisms underlying the making and evolution of animal form.<br> <p><br></p> <p> Jennifer K. Grenier is currently a senior scientist in the Microarray Group at Mirus Corporation in Madison, Wisconsin. Her scientific interests include the evolution of development, comparative genomics, and innovative technologies for functional genomics research.<br></p> <p><br></p> <p> Scott D. Weatherbee is a research fellow at the Memorial Sloan Kettering Cancer Center in New York City. He studies the developmental genetics of limb formation and patterning.</p>

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