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Epigenetics : Linking Genotype and Phenotype in Development and Evolution

By: Hallgrimsson, Benedikt, Ph.D.
Contributor(s): Hall, Brian K., Ph.D.
Material type: TextTextSeries: eBooks on Demand.Publisher: Berkeley : University of California Press, 2011Description: 1 online resource (469 p.).ISBN: 9780520948822.Subject(s): Developmental genetics | Developmental genetics | Epigenesis | Epigenesis | Evolutionary genetics | Evolutionary genetics | Genetic regulation | Genetic regulation | Phenotype | PhenotypeGenre/Form: Electronic books.Additional physical formats: Print version:: Epigenetics : Linking Genotype and Phenotype in Development and EvolutionDDC classification: 576.5/3 | 576.53 Online resources: Click here to view this ebook.
Contents:
Cover; Contents; Contributors; 1 INTRODUCTION; Part I: Historical and Philosophical Foundations; 2 A BRIEF HISTORY OF THE TERM AND CONCEPT EPIGENETICS; 3 HEURISTIC REDUCTIONISM AND THE RELATIVE SIGNIFICANCE OF EPIGENETIC INHERITANCE IN EVOLUTION; Part II: Approaches to Epigenetics; 4 THE EPIGENETICS OF GENOMIC IMPRINTING: CORE EPIGENETIC PROCESSES ARE CONSERVED IN MAMMALS, INSECTS, AND PLANTS; 5 METHYLATION MAPPING IN HUMANS; 6 ASEXUALITY AND EPIGENETIC VARIATION; 7 EPIGENESIS, PREFORMATION, AND THE HUMPTY DUMPTY PROBLEM; 8 A PRINCIPLE OF DEVELOPMENTAL INERTIA
Part III: Epigenetics of Vertebrate Organ Development9 THE ROLE OF EPIGENETICS IN NERVOUS SYSTEM DEVELOPMENT; 10 MORPHOGENESIS OF PIGMENT PATTERNS: EXPERIMENTAL AND MODELING APPROACHES; 11 EPIGENETIC INTERACTIONS OF THE CARDIAC NEURAL CREST; 12 EPIGENETICS IN BONE AND CARTILAGE DEVELOPMENT; 13 MUSCLE-BONE INTERACTIONS AND THE DEVELOPMENT OF SKELETAL PHENOTYPE: JAW MUSCLES AND THE SKULL; 14 EVOLUTION OF THE APICAL ECTODERM IN THE DEVELOPING VERTEBRATE LIMB; 15 ROLE OF SKELETAL MUSCLE IN THE EPIGENETIC SHAPING OF ORGANS, TISSUES, AND CELL FATE CHOICES
Part IV: Epigenetics in Evolution and Disease16 EPIGENETIC INTEGRATION, COMPLEXITY, AND EVOLVABILITY OF THE HEAD: RETHINKING THE FUNCTIONAL MATRIX HYPOTHESIS; 17 EPIGENETIC INTERACTIONS: THE DEVELOPMENTAL ROUTE TO FUNCTIONAL INTEGRATION; 18 EPIGENETIC CONTRIBUTIONS TO ADAPTIVE RADIATION: INSIGHTS FROM THREESPINE STICKLEBACK; 19 LEARNING, DEVELOPMENTAL PLASTICITY, AND THE RATE OF MORPHOLOGICAL EVOLUTION; 20 EPIGENETICS: ADAPTATION OR CONTINGENCY?; 21 THE EPIGENETICS OF DYSMORPHOLOGY: CRANIOSYNOSTOSIS AS AN EXAMPLE; 22 EPIGENETICS OF HUMAN DISEASE; 23 EPIGENETICS: THE CONTEXT OF DEVELOPMENT
IndexA; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z
Summary: Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. C
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Item type Current location Call number URL Status Date due Barcode
Electronic Book UT Tyler Online
Online
QH438.5 .H35 2010 (Browse shelf) http://uttyler.eblib.com/patron/FullRecord.aspx?p=674514 Available EBL674514

Cover; Contents; Contributors; 1 INTRODUCTION; Part I: Historical and Philosophical Foundations; 2 A BRIEF HISTORY OF THE TERM AND CONCEPT EPIGENETICS; 3 HEURISTIC REDUCTIONISM AND THE RELATIVE SIGNIFICANCE OF EPIGENETIC INHERITANCE IN EVOLUTION; Part II: Approaches to Epigenetics; 4 THE EPIGENETICS OF GENOMIC IMPRINTING: CORE EPIGENETIC PROCESSES ARE CONSERVED IN MAMMALS, INSECTS, AND PLANTS; 5 METHYLATION MAPPING IN HUMANS; 6 ASEXUALITY AND EPIGENETIC VARIATION; 7 EPIGENESIS, PREFORMATION, AND THE HUMPTY DUMPTY PROBLEM; 8 A PRINCIPLE OF DEVELOPMENTAL INERTIA

Part III: Epigenetics of Vertebrate Organ Development9 THE ROLE OF EPIGENETICS IN NERVOUS SYSTEM DEVELOPMENT; 10 MORPHOGENESIS OF PIGMENT PATTERNS: EXPERIMENTAL AND MODELING APPROACHES; 11 EPIGENETIC INTERACTIONS OF THE CARDIAC NEURAL CREST; 12 EPIGENETICS IN BONE AND CARTILAGE DEVELOPMENT; 13 MUSCLE-BONE INTERACTIONS AND THE DEVELOPMENT OF SKELETAL PHENOTYPE: JAW MUSCLES AND THE SKULL; 14 EVOLUTION OF THE APICAL ECTODERM IN THE DEVELOPING VERTEBRATE LIMB; 15 ROLE OF SKELETAL MUSCLE IN THE EPIGENETIC SHAPING OF ORGANS, TISSUES, AND CELL FATE CHOICES

Part IV: Epigenetics in Evolution and Disease16 EPIGENETIC INTEGRATION, COMPLEXITY, AND EVOLVABILITY OF THE HEAD: RETHINKING THE FUNCTIONAL MATRIX HYPOTHESIS; 17 EPIGENETIC INTERACTIONS: THE DEVELOPMENTAL ROUTE TO FUNCTIONAL INTEGRATION; 18 EPIGENETIC CONTRIBUTIONS TO ADAPTIVE RADIATION: INSIGHTS FROM THREESPINE STICKLEBACK; 19 LEARNING, DEVELOPMENTAL PLASTICITY, AND THE RATE OF MORPHOLOGICAL EVOLUTION; 20 EPIGENETICS: ADAPTATION OR CONTINGENCY?; 21 THE EPIGENETICS OF DYSMORPHOLOGY: CRANIOSYNOSTOSIS AS AN EXAMPLE; 22 EPIGENETICS OF HUMAN DISEASE; 23 EPIGENETICS: THE CONTEXT OF DEVELOPMENT

IndexA; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z

Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. C

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