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Diagnostic Samples : The Impact of Preanalytical Variables on the Quality of Laboratory Results

By: Guder, Walter G.
Contributor(s): Narayanan, Sheshadri | Wisser, Hermann | Zawta, Bernd.
Material type: TextTextSeries: eBooks on Demand.Publisher: Hoboken : Wiley, 2014Description: 1 online resource (126 p.).ISBN: 9783527691067.Subject(s): Diagnosis, Laboratory -- Handbooks, manuals. etc | Diagnosis, Laboratory -- Methodology | Diagnosis, Laboratory | Nursing -- Handbooks, manuals. etcGenre/Form: Electronic books.Additional physical formats: Print version:: Diagnostic Samples: From the Patient to the LaboratoryDDC classification: 616.07 | 616.07/56 Online resources: Click here to view this ebook.
Contents:
Cover Page; Title Page; Copyright Page; Preface and Acknowledgements; Contents; 1 Dream and reality; A new patient with diabetes mellitus is encountered; The right sample for the right test at the right time; This is what might happen in reality; What happened to Mrs Haseltine's samples?; Why was the result of the glucose tolerance test inconclusive?; Why was potassium elevated and glucose normal in the venous specimen?; 2 Something unavoidable; Age; Race; Gender; Pregnancy; 3 Changing habits; Diet; Starvation; Mechanisms; Recommendation; Exercise; Altitude
4 May I take coffee, smoke or drink before blood sampling?Caffeine; Effects of smoking; Alcohol; Addictive drugs; 5 What if I take herbs?; Herbs as the origin of pharmacy; Beneficial versus toxic herb effects; Effect of orally administered herbs on laboratory results; 6 When to test?; Influence of circadian rhythm (284); Analytes may change during the menstrual cycle (312); Why has blood to be taken 12 hours after the last meal? (82, 312); Timing with regard to diagnostic and therapeutic processes; 7 Sampling during infusion therapy?
Implausible laboratory results after diagnostic and therapeutic intervention?Operations; Infusions, transfusions; Sampling from catheters; Mental stress; 8 Sampling in the supine or upright position?; Posture; Tourniquet; 9 What site for sampling blood?; Phlebotomy; Quality of sample; How much blood is needed?; Sampling from artery; Sampling with catheter; 10 Blood from the skin; 11 Did the lab mix up my sample?; Name or number?; Techniques of identification; Direct versus indirect sample identification in the laboratory; 12 A precious sample
Which specific aspects of CSF sampling are important?What about storage and transport?; Special hints for CSF sampling; CSF from other sources; 13 A sample that is nearly always available; Urine; Saliva /oral fluid; 14 Plasma or serum?; What advantages does plasma have over serum?; What are the disadvantages of plasma relative to serum?; Types of plasma; 15 Take a lavender tube!; Additives; Heparin; EDTA; Citrate; Glycolytic inhibitors; Preservation of cells; 16 Fax me a sample; Effects of time and temperature during transport; 17 Samples in transit; Transport categories; Package
18 How to keep a sample „fresh"Ten rules and some recommendations; Eight special rules and some more useful recommendations; 19 What has to be done on specimen arrival?; Centrifugation; Sample handling after centrifugation; 20 Continuous or batchwise?; Robotics; 21 Safety aspects during the preanalytical phase; Disposal of needles and other sharp objects; Tube and sample disposal; Chemicals; 22 What is needed before blood transfusion?; Ensuring patient and sample identity (6, 36, 84); The right sample; Storage of blood for transfusion; What has to be done before transfusion?
23 Why a separate tube for the coagulation test?
Summary: This fourth, updated edition contains the latest developments in preanalytical knowledge. An international team of authors summarizes the information on biological influences, analytical interferences and on the variables affecting the collection, transport and storage, as well as preparation of samples. In so doing, they cover age, gender, race, pregnancy, diet, exercise and altitude, plus the effects of stimulants and drugs. National and international standards are described for sampling procedures, transport, sample identification and all safety aspects, while quality assurance procedures a
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Electronic Book UT Tyler Online
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Cover Page; Title Page; Copyright Page; Preface and Acknowledgements; Contents; 1 Dream and reality; A new patient with diabetes mellitus is encountered; The right sample for the right test at the right time; This is what might happen in reality; What happened to Mrs Haseltine's samples?; Why was the result of the glucose tolerance test inconclusive?; Why was potassium elevated and glucose normal in the venous specimen?; 2 Something unavoidable; Age; Race; Gender; Pregnancy; 3 Changing habits; Diet; Starvation; Mechanisms; Recommendation; Exercise; Altitude

4 May I take coffee, smoke or drink before blood sampling?Caffeine; Effects of smoking; Alcohol; Addictive drugs; 5 What if I take herbs?; Herbs as the origin of pharmacy; Beneficial versus toxic herb effects; Effect of orally administered herbs on laboratory results; 6 When to test?; Influence of circadian rhythm (284); Analytes may change during the menstrual cycle (312); Why has blood to be taken 12 hours after the last meal? (82, 312); Timing with regard to diagnostic and therapeutic processes; 7 Sampling during infusion therapy?

Implausible laboratory results after diagnostic and therapeutic intervention?Operations; Infusions, transfusions; Sampling from catheters; Mental stress; 8 Sampling in the supine or upright position?; Posture; Tourniquet; 9 What site for sampling blood?; Phlebotomy; Quality of sample; How much blood is needed?; Sampling from artery; Sampling with catheter; 10 Blood from the skin; 11 Did the lab mix up my sample?; Name or number?; Techniques of identification; Direct versus indirect sample identification in the laboratory; 12 A precious sample

Which specific aspects of CSF sampling are important?What about storage and transport?; Special hints for CSF sampling; CSF from other sources; 13 A sample that is nearly always available; Urine; Saliva /oral fluid; 14 Plasma or serum?; What advantages does plasma have over serum?; What are the disadvantages of plasma relative to serum?; Types of plasma; 15 Take a lavender tube!; Additives; Heparin; EDTA; Citrate; Glycolytic inhibitors; Preservation of cells; 16 Fax me a sample; Effects of time and temperature during transport; 17 Samples in transit; Transport categories; Package

18 How to keep a sample „fresh"Ten rules and some recommendations; Eight special rules and some more useful recommendations; 19 What has to be done on specimen arrival?; Centrifugation; Sample handling after centrifugation; 20 Continuous or batchwise?; Robotics; 21 Safety aspects during the preanalytical phase; Disposal of needles and other sharp objects; Tube and sample disposal; Chemicals; 22 What is needed before blood transfusion?; Ensuring patient and sample identity (6, 36, 84); The right sample; Storage of blood for transfusion; What has to be done before transfusion?

23 Why a separate tube for the coagulation test?

This fourth, updated edition contains the latest developments in preanalytical knowledge. An international team of authors summarizes the information on biological influences, analytical interferences and on the variables affecting the collection, transport and storage, as well as preparation of samples. In so doing, they cover age, gender, race, pregnancy, diet, exercise and altitude, plus the effects of stimulants and drugs. National and international standards are described for sampling procedures, transport, sample identification and all safety aspects, while quality assurance procedures a

Description based upon print version of record.

Author notes provided by Syndetics

Until Jan 2003 Prof. Dr. Walter G. Guder was Director of the Institute of Clinical Chemistry, Bogenhausen Community Hospital Munich and Professor of Clinical Biochemistry at the Ludwig-Maximilians-University of Munich. He studied medicine in Cologne, Tübingen and Munich. He served as President of the German Society of Clinical Chemistry and was Chairman of the Working Group on Preanalytical Quality. He is Editor of the "Laborbuch für Klinik und Praxis" and Administrator of the Internet Program www.diagnosticsample.com. <p> Prof. Dr. Sheshadri Narayanan is an Adjunct Clinical Professor of Pathology and Laboratory Medicine at the Weill Medical College of Cornell University, New York City. He is a diplomate of the American Board of Clinical Chemistry and is qualified to act as Clinical Laboratory Director in the States of New York and New Jersey. Besides the many publications he has also authored a book on "Principles and Applications of Laboratory Instrumentation" and co-authored with Prof. Donald S. Young a book on "Effects of Herbs and Natural Products on Clinical Laboratory Tests".</p> <p> Prof. Dr. Dr. Hermann Wisser studied medicine and chemistry at the universities of Marburg, Göttingen and Mainz. He completed his education in laboratory medicine in Munich and Hannover. Thereafter he served as head of the Department of Laboratory Medicine of the Robert Bosch Hospital in Stuttgart and of the Institut of Clinical Chemistry of the University Hospital Mannheim. He was President of the German Society of Clinical Chemistry and President of the Forum of the European Societies of Clinical Chemistry.</p> <p>Until he died in 2004 Dr. Bernd Zawta was Head of the Department of Scientific Customer Support and Public Relations of Roche Diagnostics GmbH. He studied chemistry at the Technical University, Dresden, where he made his thesis on "The chromatography of steroid hormones". He was editor of more than 20 brochures on the diagnostic application of tests in human diseases. Dr. Zawta served as WHO consultant in Mongolia in 1985. He died just before finishing a teaching program "Focus Patient Sample" together with Guder, Hagemann and Wisser.</p>

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