Normal view MARC view ISBD view

Quasispecies.

By: Domingo, Esteban.
Contributor(s): Schuster, Peter.
Material type: TextTextSeries: eBooks on Demand.Current Topics in Microbiology and Immunology: Publisher: Cham : Springer International Publishing, 2016Description: 1 online resource (360 p.).ISBN: 9783319238982.Subject(s): ImmunologyGenre/Form: Electronic books.Additional physical formats: Print version:: Quasispecies: From Theory to Experimental SystemsDDC classification: 610 Online resources: Click here to view this ebook.
Contents:
Foreword -- Preface -- Contents -- 453 What Is a Quasispecies? Historical Origins and Current Scope -- Abstract -- 1 Evolution on the Cross-Road of Chemistry and Biology -- 2 A Few Quantitative Relations -- 3 What Happens Beyond Error Threshold? -- 4 Origin of the Experimental Quasispecies Concept -- 5 Quasispecies Theory and Experimental RNA Virus Quasispecies -- 6 Extensions of Quasispecies to Non-viral Systems -- 7 Limitations and Strengths of the Quasispecies Concept -- Acknowledgments -- References -- 454 The Nucleation of Semantic Information in Prebiotic Matter -- Abstract
1 Life = Matter + Information -- 2 Natural Selection of Information -- 3 Evolutionary Optimisation of Information -- 4 The Context-Dependence of Semantic Information -- 5 Overcoming Information Barriers -- 6 Deciphering the Semantic Code of Evolution -- References -- 470 Evolution of RNA-Based Networks -- Abstract -- 1 From Replication to Fitness Landscapes -- 1.1 The Quasispecies -- 1.2 Molecular Replicators -- 1.3 Quantifying Natural Fitness Landscapes -- 1.4 Computer Models of RNA Evolution -- 2 Autocatalytic Networks -- 2.1 The Bioinformatics of RNA-RNA Interactions -- 2.2 Replicator Networks
2.3 Evolution of Autocatalytic Networks -- 2.4 Distributed Autocatalysis -- References -- 469 Quasispecies on Fitness Landscapes -- Abstract -- 1 Fitness Landscapes -- 2 Sequence Structure Mappings -- 3 Mutations and Population Dynamics -- 4 Quasispecies and Error Thresholds -- 5 Conclusions and Perspectives -- 6 Color Code for Sequences and Classes -- Acknowledgements -- References -- 471 Mathematical Models of Quasi-Species Theory and Exact Results for the Dynamics -- Abstract -- 1 Introduction -- 2 The Definition of the Models -- 2.1 Eigen Model -- 2.2 The Discrete-Time Eigen Model
2.3 Crow-Kimura Model -- 2.4 The Solution of the Models -- 3 Relaxation on a Single-Peak Fitness Landscape -- 4 The Dynamics of Crow-Kimura Model with a Symmetric Fitness Landscape -- 4.1 HJE for the Crow-Kimura Model -- 4.2 The Solution of HJE by the Methods of Characteristics -- 4.3 The Flat Original Distribution -- 5 The Dynamics of the Eigen Model -- 6 Discussion -- References -- 456 Theoretical Models of Generalized Quasispecies -- Abstract -- References -- 463 Theories of Lethal Mutagenesis: From Error Catastrophe to Lethal Defection -- Abstract -- 1 Introduction
2 The Error Threshold and the Error Catastrophe -- 2.1 The Limits of the Error Catastrophe -- 3 Mutation-Selection-Based Models -- 3.1 Lethality, Extinction and Error Catastrophe -- 4 Lethal Defection -- 4.1 Stochastic Extinction Model -- 4.2 Interference, Complementation and Lethal Defection -- 5 Problems of Lethal Mutagenesis -- 5.1 Resistance and Survival of Flattest -- 5.2 Sublethal Mutagenesis -- 6 Concluding Remarks -- Acknowledgments -- References -- 462 Estimating Fitness of Viral Quasispecies from Next-Generation Sequencing Data -- Abstract -- 1 Introduction -- 1.1 Viral Evolution
1.2 Fitness Landscapes
Tags from this library: No tags from this library for this title. Log in to add tags.
Item type Current location Call number URL Status Date due Barcode
Electronic Book UT Tyler Online
Online
R-RZ (Browse shelf) http://uttyler.eblib.com/patron/FullRecord.aspx?p=4454247 Available EBL4454247

Foreword -- Preface -- Contents -- 453 What Is a Quasispecies? Historical Origins and Current Scope -- Abstract -- 1 Evolution on the Cross-Road of Chemistry and Biology -- 2 A Few Quantitative Relations -- 3 What Happens Beyond Error Threshold? -- 4 Origin of the Experimental Quasispecies Concept -- 5 Quasispecies Theory and Experimental RNA Virus Quasispecies -- 6 Extensions of Quasispecies to Non-viral Systems -- 7 Limitations and Strengths of the Quasispecies Concept -- Acknowledgments -- References -- 454 The Nucleation of Semantic Information in Prebiotic Matter -- Abstract

1 Life = Matter + Information -- 2 Natural Selection of Information -- 3 Evolutionary Optimisation of Information -- 4 The Context-Dependence of Semantic Information -- 5 Overcoming Information Barriers -- 6 Deciphering the Semantic Code of Evolution -- References -- 470 Evolution of RNA-Based Networks -- Abstract -- 1 From Replication to Fitness Landscapes -- 1.1 The Quasispecies -- 1.2 Molecular Replicators -- 1.3 Quantifying Natural Fitness Landscapes -- 1.4 Computer Models of RNA Evolution -- 2 Autocatalytic Networks -- 2.1 The Bioinformatics of RNA-RNA Interactions -- 2.2 Replicator Networks

2.3 Evolution of Autocatalytic Networks -- 2.4 Distributed Autocatalysis -- References -- 469 Quasispecies on Fitness Landscapes -- Abstract -- 1 Fitness Landscapes -- 2 Sequence Structure Mappings -- 3 Mutations and Population Dynamics -- 4 Quasispecies and Error Thresholds -- 5 Conclusions and Perspectives -- 6 Color Code for Sequences and Classes -- Acknowledgements -- References -- 471 Mathematical Models of Quasi-Species Theory and Exact Results for the Dynamics -- Abstract -- 1 Introduction -- 2 The Definition of the Models -- 2.1 Eigen Model -- 2.2 The Discrete-Time Eigen Model

2.3 Crow-Kimura Model -- 2.4 The Solution of the Models -- 3 Relaxation on a Single-Peak Fitness Landscape -- 4 The Dynamics of Crow-Kimura Model with a Symmetric Fitness Landscape -- 4.1 HJE for the Crow-Kimura Model -- 4.2 The Solution of HJE by the Methods of Characteristics -- 4.3 The Flat Original Distribution -- 5 The Dynamics of the Eigen Model -- 6 Discussion -- References -- 456 Theoretical Models of Generalized Quasispecies -- Abstract -- References -- 463 Theories of Lethal Mutagenesis: From Error Catastrophe to Lethal Defection -- Abstract -- 1 Introduction

2 The Error Threshold and the Error Catastrophe -- 2.1 The Limits of the Error Catastrophe -- 3 Mutation-Selection-Based Models -- 3.1 Lethality, Extinction and Error Catastrophe -- 4 Lethal Defection -- 4.1 Stochastic Extinction Model -- 4.2 Interference, Complementation and Lethal Defection -- 5 Problems of Lethal Mutagenesis -- 5.1 Resistance and Survival of Flattest -- 5.2 Sublethal Mutagenesis -- 6 Concluding Remarks -- Acknowledgments -- References -- 462 Estimating Fitness of Viral Quasispecies from Next-Generation Sequencing Data -- Abstract -- 1 Introduction -- 1.1 Viral Evolution

1.2 Fitness Landscapes

Description based upon print version of record.

Author notes provided by Syndetics

Esteban Domingo is a professor at the Spanish Research Council at Centro de Biología Molecular Severo Ochoa (Madrid) and President of the Spanish Society of Virology. He is a member of EMBO and Real Academía de Ciencias Exactas, Físicas y Naturales. Peter Schuster, em. professor of University of Vienna is a member of Leopoldina, Nationale Akademie der Wissenschaften, National Academy of Sciences USA, European Academy of Sciences and Arts and several other institutions. He worked together with Manfred Eigen and developed together with him the concepts of "quasispecies" and "hypercycles".

There are no comments for this item.

Log in to your account to post a comment.